An In Vitro Model for Assessing Corneal Keratocyte Spreading and Migration on Aligned Fibrillar Collagen
نویسندگان
چکیده
منابع مشابه
Growth factor regulation of corneal keratocyte differentiation and migration in compressed collagen matrices.
PURPOSE To evaluate a novel 3D culture model of the corneal stroma and apply it to investigate how key wound-healing growth factors regulate the mechanics of corneal keratocyte migration. METHODS Rabbit corneal keratocytes were seeded within collagen matrices that were compacted using external compression. Six-millimeter-diameter buttons were then incubated in media supplemented with 10% FBS,...
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ژورنال
عنوان ژورنال: Journal of Functional Biomaterials
سال: 2018
ISSN: 2079-4983
DOI: 10.3390/jfb9040054